HDAC2 (2D9) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3020-50, MB3020-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q92769

Host: Mouse

Reactivity: Human, Mouse, Rat,Monkey

Applications: WB,ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of HDAC2 in THP-1, SH-SY5Y, K562, COS7, C6, 3T3 and HelaLysates using HDAC2 antibody.

Bioworld Molecular Weight: Calculated MW: 55 kDa; Observed MW: 60 kDa

Specificity: IgG2b

Alternative Name: HDAC2; Histone deacetylase 2; HD2

Immunogen: Purified recombinant human HDAC2 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified