Obagi Medical Retinol + PHA

Refining Night Cream 

Advanced dual-action formula 

Retinol + PHA Refining Night Cream works overnight to help refine skin texture and tone while reducing the appearance of blemishes, fine lines, and wrinkles for a visibly resurfaced, smoother, clearer, and more even-looking complexion in just 4 weeks*.

Formulated with Entrapped Retinol powered by slow-release technology for optimized delivery into deeper layers of the skin to encourage skin cell turnover, and Polyhydroxy Acid (Gluconolactone) to provide gentle yet effective exfoliation on the surface of the skin, plus eight nourishing ingredients to keep skin hydrated, this overnight cream has the unique ability to help renew and enhance the appearance of your complexion.

Clinically proven to:

• Visibly improve skin smoothness by 29%.*
• Visibly improve skin tone evenness by 10%.*
• Be well-tolerated by the skin.*

*Results based on a 2024 -2025 8-week clinical test. Data on file at Obagi Cosmeceuticals LLC.

A keratolytic agent commonly referred to as Vitamin A. This gold-standard ingredient is known to help unclog pores, reduce excess surface oil, resurface signs of aging, minimize formation of blemishes, and accelerate skin cell turnover for a smoother, brighter complexion, and improved skin texture over time. The innovative slow-release technology uses a microspheres to entrap Retinol, helping to minimize exposure to light and oxygen while ensuring its gradual release into deeper layers of the skin over time, enhancing stability and minimizing the irritation that is typically associated with acids & Vitamin A derivatives. 

POLYHYDROXY ACID (PHA – GLUCONOLACTONE) 

A chemical exfoliant that belongs to the hydroxy acids family that exfoliates, smooths skin texture, helps boost hydration, and improves skin tone. 

SODIUM HYALURONATE

A humectant that is a derivative of hyaluronic acid (HA) with intense hydration capabilities. 

VITAMIN E (TOCOPHEROL)

An antioxidant that helps to protect against oxidative damage and helps to nourish skin.

SQUALANE

A lipid that helps improve hydration and texture while supporting a healthy skin barrier by mimicking skin’s