Will this hose work for both coolant and boost applications?

Yes. Silicone construction tolerates coolant loops and turbo/supercharger intake charge air without degradation. If you're running boost, confirm your system pressure stays within silicone's safe operating range for your specific setup.

Do I need hose clamps?

You'll need clamps rated for the hose diameters you're connecting to — typically 3-inch and 3.5-inch band clamps. Clamps are not included, so source them separately based on your plumbing layout.

Can I cut or modify this hose to fit a tighter space?

Cutting silicone hose is straightforward, but you lose the 90-degree geometry and bend radius engineering. If your space requires a different angle or length, custom hose from a local fabricator often costs less than trial-and-error modifications.