Will this hose work for both coolant and boost lines?

Yes. The 3-ply silicone core handles coolant temps, vacuum draw, and moderate boost pressure. For high-boost setups pushing over 20 psi sustained, confirm your system pressure against silicone's rated limits.

Do I need clamps, and what size?

Clamps are not included. You'll need hose clamps sized for 2.00" OD — typically 2-1/4" or 2-1/2" worm-drive or band clamps, depending on your fitting design.

Can I cut this hose to a shorter length?

Absolutely. Use a sharp utility knife or hose cutter for a clean edge. After cutting, let the exposed end sit for a few minutes before installing to avoid silicone dust in your coolant or intake.