Recombinant Human Syndecan-1/SDC1 Protein (Fc Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH033514-10, PKSH033514-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Syndecan-1; SDC1

Target Symptom: Syndecan-1; SYND1; CD138; SDC1; SDC

Research Area: Signal Transduction; Neuroscience; Cancer; metabolism; Stem cells

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-Fc

UNIProt ID: P18827

Accession: P18827

Background: Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding; cell signaling; and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence; and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation; cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.

Sequence: Gln18-Glu251(Leu136Gln)

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 51 kDa

Observed MW: 80-90 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only